Intermittent fasting prompted recovery from dextran sulfate sodium-induced colitis in mice

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Intermittent fasting prompted recovery from dextran sulfate sodium-induced colitis in mice

Fasting-refeeding in mice induces transient hyperproliferation of colonic epithelial cells, which is dependent on the lactate produced as a metabolite of commensal bacteria. We attempted to manipulate colonic epithelial cell turnover with intermittent fasting to prompt recovery from acute colitis. Acute colitis was induced in C57BL/6 mice by administration of dextran sulfate sodium in the drink...

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ژورنال

عنوان ژورنال: Journal of Clinical Biochemistry and Nutrition

سال: 2017

ISSN: 0912-0009,1880-5086

DOI: 10.3164/jcbn.17-9